iPTMnet Report for P50452 (SERPINB8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50452 / SPB8_HUMAN
Protein Name Serpin B8
Gene Name Name: SERPINB8
Synonyms:PI8;
Organism Homo sapiens (Human)

PRO ID PR:P50452
DAG View
PRO Name serpin B8 (human)
Definition A serpin B8 that is encoded in the genome of human.
Short Label hSERPINB8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50452 (SERPINB8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation IEDB 35494241
T50 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
R87 Methylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
K178 Methylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S49 N49 Biomuta DOID:4159 / skin cancer [ cosmic ]
R87 I87 Biomuta DOID:1319 / brain cancer [ icgc ]
K143 E143 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K258 N258 Biomuta DOID:363 / uterine cancer [ icgc ]
S262 R262 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K263 N263 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K312 M312 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S338 F338 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]