iPTMnet Report for P50440 (GATM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50440 / GATM_HUMAN
Protein Name Glycine amidinotransferase, mitochondrial precursor
Gene Name Name: GATM
Synonyms:AGAT;
Organism Homo sapiens (Human)

PRO ID PR:P50440
DAG View
PRO Name glycine amidinotransferase, mitochondrial (human)
Definition A glycine amidinotransferase, mitochondrial that is encoded in the genome of human.
Short Label hGATM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50440 (GATM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus   UniProt 24275569
S49 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y100 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
K385 Acetylation PhosphoSitePlus   UniProt 19608861
T417 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S38 Phosphorylation HPRD 20166139, 18077418
T39 Phosphorylation HPRD 20166139, 18077418
T43 Phosphorylation HPRD 20166139
S45 Phosphorylation HPRD 20166139
S46 Phosphorylation HPRD 20166139, 18077418
S49 Phosphorylation HPRD 20166139
S231 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T43 M43 Biomuta DOID:363 / uterine cancer [ icgc ]
S46 Y46 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y203 C203 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S231 F231 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S231 C231 Biomuta DOID:1324 / lung cancer [ cosmic ]