iPTMnet Report for P50406 (HTR6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P50406 / 5HT6R_HUMAN
Protein Name 5-hydroxytryptamine receptor 6
Gene Name Name: HTR6
Organism Homo sapiens (Human)

PRO ID PR:P50406
DAG View
PRO Name 5-hydroxytryptamine receptor 6 (human)
Definition A 5-hydroxytryptamine receptor 6 that is encoded in the genome of human.
Short Label hHTR6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50406 (HTR6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y125 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
S193 Phosphorylation IEDB 35494241
K258 Methylation PhosphoSitePlus
K262 Methylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S350 L350 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]