Protein Information

Cytoscape View


UniProt AC / UniProt ID P50395 / GDIB_HUMAN
Protein Name Rab GDP dissociation inhibitor beta
Gene Name Name: GDI2
Synonyms:RABGDIB;
Organism Homo sapiens (Human)

PRO ID PR:P50395
DAG View
PRO Name Rab GDP dissociation inhibitor beta (human)
Definition A Rab GDP dissociation inhibitor beta that is encoded in the genome of human.
Short Label hGDI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P50395 (GDI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
Y5 Phosphorylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
R35 Methylation PhosphoSitePlus
Y38 Phosphorylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
K54 Acetylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S61 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
R68 Methylation PhosphoSitePlus
R70 Methylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus   UniProt 19608861
K112 Methylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K153 Acetylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K174 Acetylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
Y203 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107, 16497976
T205 Phosphorylation PhosphoSitePlus
K210 Acetylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
K221 Methylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K269 Acetylation PhosphoSitePlus   UniProt 19608861
K269 Sumoylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K288 Acetylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K364 Acetylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus   UniProt 24275569
S384 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K435 Acetylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation HPRD 17322306, 19413330, 18669648, ...20068231, 20230923
Y111 Phosphorylation HPRD 20068231
Y197 Phosphorylation HPRD 16497976
Y203 Phosphorylation HPRD 18083107, 16497976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K29 E29 Biomuta DOID:3963 / thyroid carcinoma [ tcga ]
Y38 * Biomuta DOID:3571 / liver cancer [ icgc ]
K164 R164 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, tcga ]
K253 N253 Biomuta DOID:1324 / lung cancer [ cosmic ]
S330 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y349 C349 Biomuta DOID:10534 / stomach cancer [ tcga ]
S401 P401 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]