iPTMnet Report for P50135 (HNMT)
Protein Information
| UniProt AC / UniProt ID | P50135 / HNMT_HUMAN |
| Protein Name | Histamine N-methyltransferase |
| Gene Name | Name: HNMT |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P50135 |
| PRO Name | histamine N-methyltransferase (human) |
| Definition | A histamine N-methyltransferase that is encoded in the genome of human. |
| Short Label | hHNMT |
| Category | organism-gene |
DAG ViewP50135 (HNMT) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T284 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S114 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S78 | L78 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K99 | E99 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
