Protein Information

Cytoscape View

UniProt AC / UniProt ID P49903 / SPS1_HUMAN
Protein Name Selenide, water dikinase 1
Gene Name Name: SEPHS1
Organism Homo sapiens (Human)

PRO ID PR:P49903
DAG View
PRO Name selenide, water dikinase 1 (human)
Definition A selenide, water dikinase 1 that is encoded in the genome of human.
Short Label hSEPHS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P49903 (SEPHS1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S6 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K341 Acetylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S392 Phosphorylation HPRD 19413330, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 C6 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
Y345 N345 Biomuta DOID:2394 / ovarian cancer [ tcga ]
S392 F392 Biomuta DOID:363 / uterine cancer [ tcga ]