Protein Information

Cytoscape View


UniProt AC / UniProt ID P49863 / GRAK_HUMAN
Protein Name Granzyme K precursor
Gene Name Name: GZMK
Synonyms:TRYP2;
Organism Homo sapiens (Human)

PRO ID PR:P49863
DAG View
PRO Name granzyme K (human)
Definition A granzyme K that is encoded in the genome of human.
Short Label hGZMK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49863 (GZMK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y17 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
Y186 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y187 Phosphorylation HPRD   PhosphoSitePlus 18452278
T252 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T96 A96 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T252 N252 Biomuta DOID:1324 / lung cancer [ tcga ]
S256 G256 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]