iPTMnet Report for P49863 (GZMK)
Protein Information
| UniProt AC / UniProt ID | P49863 / GRAK_HUMAN |
| Protein Name | Granzyme K precursor |
| Gene Name | Name: GZMK Synonyms:TRYP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P49863 |
| PRO Name | granzyme K (human) |
| Definition | A granzyme K that is encoded in the genome of human. |
| Short Label | hGZMK |
| Category | organism-gene |
DAG ViewP49863 (GZMK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S161 | Phosphorylation | score1 | IEDB | 35494241 | ||
| Y186 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| Y187 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| T252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T263 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S161 | L161 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S161 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S256 | G256 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
