Protein Information

Cytoscape View


UniProt AC / UniProt ID P49821 / NDUV1_HUMAN
Protein Name NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor
Gene Name Name: NDUFV1
Synonyms:UQOR1;
Organism Homo sapiens (Human)

PRO ID PR:P49821
DAG View
PRO Name NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (human)
Definition An NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial that is encoded in the genome of human.
Short Label hNDUFV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49821 (NDUFV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K29 Ubiquitination PhosphoSitePlus
R40 Methylation PhosphoSitePlus
K64 Acetylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K81 Acetylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
R88 Methylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
R257 Methylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K375 Acetylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S464 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K66 R66 Biomuta DOID:1324 / lung cancer [ tcga ]
R88 H88 Biomuta DOID:363 / uterine cancer [ tcga ]
S323 Y323 Biomuta DOID:1324 / lung cancer [ tcga ]
K365 E365 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K394 N394 Biomuta DOID:363 / uterine cancer [ tcga ]