iPTMnet Report for P49748 (ACADVL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49748 / ACADV_HUMAN
Protein Name Very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor
Gene Name Name: ACADVL
Synonyms:VLCAD;
Organism Homo sapiens (Human)

PRO ID PR:P49748
DAG View
PRO Name very long-chain specific acyl-CoA dehydrogenase, mitochondrial (human)
Definition A very long-chain specific acyl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hACADVL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49748 (ACADVL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 O-Glycosylation GlyGen 33214551, 34725712, 35083852, ...33465208, 28510447
S52 O-Glycosylation GlyGen 33214551, 34725712, 35083852, ...33465208, 28510447
S54 Phosphorylation PhosphoSitePlus
T61 O-Glycosylation GlyGen 33465208
K71 Acetylation PhosphoSitePlus
K239 Acetylation PhosphoSitePlus   UniProt 19608861
K247 Methylation PhosphoSitePlus
K276 Acetylation PhosphoSitePlus
K278 Acetylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
K298 Acetylation PhosphoSitePlus
K299 Acetylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
K331 Acetylation PhosphoSitePlus   UniProt 19608861
T364 Phosphorylation PhosphoSitePlus
K372 Acetylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K482 Acetylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K507 Acetylation PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus   UniProt 23186163
S522 Phosphorylation PhosphoSitePlus   UniProt 23186163
S586 Phosphorylation PhosphoSitePlus
Y631 Phosphorylation PhosphoSitePlus
K635 Sumoylation PhosphoSitePlus
K639 Acetylation PhosphoSitePlus
K639 Ubiquitination PhosphoSitePlus
R644 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S489 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S467 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K71 N71 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K247 N247 Biomuta DOID:363 / uterine cancer [ icgc ]
K276 N276 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S517 N517 Biomuta DOID:4362 / cervical cancer [ icgc ]
R644 Q644 Biomuta DOID:10534 / stomach cancer [ cosmic ]