iPTMnet Report for P49748 (ACADVL)
Protein Information
UniProt AC / UniProt ID | P49748 / ACADV_HUMAN |
Protein Name | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor |
Gene Name | Name: ACADVL Synonyms:VLCAD; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P49748 |
PRO Name | very long-chain specific acyl-CoA dehydrogenase, mitochondrial (human) |
Definition | A very long-chain specific acyl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human. |
Short Label | hACADVL |
Category | organism-gene |
P49748 (ACADVL) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S21 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 35083852, ... | ||
S52 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 35083852, ... | ||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
T61 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
K71 | Acetylation | score1 | PhosphoSitePlus | |||
K239 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K247 | Methylation | score1 | PhosphoSitePlus | |||
K276 | Acetylation | score1 | PhosphoSitePlus | |||
K278 | Acetylation | score1 | PhosphoSitePlus | |||
R286 | Methylation | score1 | PhosphoSitePlus | |||
K298 | Acetylation | score1 | PhosphoSitePlus | |||
K299 | Acetylation | score1 | PhosphoSitePlus | |||
S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
K331 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T364 | Phosphorylation | score1 | PhosphoSitePlus | |||
K372 | Acetylation | score1 | PhosphoSitePlus | |||
K372 | Ubiquitination | score1 | PhosphoSitePlus | |||
K482 | Acetylation | score1 | PhosphoSitePlus | |||
S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
S489 | Phosphorylation | score1 | PhosphoSitePlus | |||
K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
K507 | Acetylation | score1 | PhosphoSitePlus | |||
K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
S517 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S522 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y631 | Phosphorylation | score1 | PhosphoSitePlus | |||
K635 | Sumoylation | score1 | PhosphoSitePlus | |||
K639 | Acetylation | score1 | PhosphoSitePlus | |||
K639 | Ubiquitination | score1 | PhosphoSitePlus | |||
R644 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K71 | N71 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K247 | N247 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K276 | N276 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S517 | N517 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
R644 | Q644 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |