iPTMnet Report for P49715 (CEBPA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49715 / CEBPA_HUMAN
Protein Name CCAAT/enhancer-binding protein alpha
Gene Name Name: CEBPA
Synonyms:CEBP;
Organism Homo sapiens (Human)

PRO ID PR:P49715
DAG View
PRO Name CCAAT/enhancer-binding protein alpha (human)
Definition A CCAAT/enhancer-binding protein alpha that is encoded in the genome of human.
Short Label hCEBPA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49715 (CEBPA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation P06493 (CDK1) , P28482 (MAPK1) , P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 19544470, 22212957, 14701740, ...22797303, 20101026, 22349414, 16446383, 21912254, 20516642, 16807249, 23814099, 22474248, 25753223
R35 Methylation PhosphoSitePlus
R156 Methylation PhosphoSitePlus
K161 Acetylation PhosphoSitePlus   UniProt 19608861
K161 Sumoylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
R165 Methylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus   UniProt 15107404
S234 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus 22797303, 20516642
S266 Phosphorylation PhosphoSitePlus
S277 Phosphorylation RLIMS-P 1527059
K298 Acetylation PhosphoSitePlus
S299 Phosphorylation RLIMS-P 1527059
K302 Acetylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K326 Acetylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T226 Phosphorylation P49841 (GSK3B) HPRD 10567568
T230 Phosphorylation P49841 (GSK3B) HPRD 10567568
S234 Phosphorylation HPRD 10567568


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 R21 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S21 G21 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S190 P190 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
K298 Q298 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K298 N298 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K326 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]