iPTMnet Report for P49642 (PRIM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49642 / PRI1_HUMAN
Protein Name DNA primase small subunit
Gene Name Name: PRIM1
Organism Homo sapiens (Human)

PRO ID PR:P49642
DAG View
PRO Name DNA primase small subunit (human)
Definition A DNA primase small subunit that is encoded in the genome of human.
Short Label hPRIM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49642 (PRIM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22223895
T3 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y16 Phosphorylation HPRD 20068231
K68 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation HPRD   PhosphoSitePlus 20068231
S190 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
Y391 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K221 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S387 N387 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]