iPTMnet Report for P49641 (MAN2A2)
Protein Information
| UniProt AC / UniProt ID | P49641 / MA2A2_HUMAN |
| Protein Name | Alpha-mannosidase 2x |
| Gene Name | Name: MAN2A2 Synonyms:MANA2X; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P49641 |
| PRO Name | alpha-mannosidase 2x (human) |
| Definition | An alpha-mannosidase 2x that is encoded in the genome of human. |
| Short Label | hMAN2A2 |
| Category | organism-gene |
DAG ViewP49641 (MAN2A2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S45 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S107 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N305 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S516 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S670 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y769 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S783 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y923 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T939 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1093 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S823 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S826 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T850 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T852 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S783 | N783 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| N1093 | S1093 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
