iPTMnet Report for P49593 (PPM1F)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49593 / PPM1F_HUMAN
Protein Name Protein phosphatase 1F
Gene Name Name: PPM1F
Synonyms:KIAA0015,POPX2;
Organism Homo sapiens (Human)

PRO ID PR:P49593
DAG View
PRO Name protein phosphatase 1F (human)
Definition A protein phosphatase 1F that is encoded in the genome of human.
Short Label hPPM1F
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49593 (PPM1F) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K70 Ubiquitination PhosphoSitePlus
R100 Methylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
T448 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S454 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P04637 (TP53) S20 P49593 (PPM1F) unknown eFIP 27769050


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R100 K100 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T448 N448 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T448 I448 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc, tcga ]