Protein Information

Cytoscape View

UniProt AC / UniProt ID P49441 / INPP_HUMAN
Protein Name Inositol polyphosphate 1-phosphatase
Gene Name Name: INPP1
Organism Homo sapiens (Human)

PRO ID PR:P49441
DAG View
PRO Name inositol polyphosphate 1-phosphatase (human)
Definition An inositol polyphosphate 1-phosphatase that is encoded in the genome of human.
Short Label hINPP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P49441 (INPP1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K74 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
R283 Methylation PhosphoSitePlus
S317 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18220336

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 F81 Biomuta DOID:1115 / sarcoma [ tcga ]
R283 L283 Biomuta DOID:3571 / liver cancer [ icgc ]
R283 C283 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
R283 H283 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1324 / lung cancer [ tcga ]