iPTMnet Report for P49418 (AMPH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49418 / AMPH_HUMAN
Protein Name Amphiphysin
Gene Name Name: AMPH
Synonyms:AMPH1;
Organism Homo sapiens (Human)

PRO ID PR:P49418
DAG View
PRO Name amphiphysin (human)
Definition An amphiphysin that is encoded in the genome of human.
Short Label hAMPH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49418 (AMPH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
T6 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
K11 Acetylation PhosphoSitePlus
K15 Acetylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K141 Acetylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus   RLIMS-P 18761055
S262 Phosphorylation PhosphoSitePlus   Signor 15262992
S262 Phosphorylation Q13627 (DYRK1A) Signor 15262992
S268 Phosphorylation PhosphoSitePlus
S272 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11113134, 15262992
S272 Phosphorylation P06493 (CDK1) PhosphoSitePlus 11113134
S272 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 11113134
S272 Phosphorylation Q13627 (DYRK1A) Signor 15262992
S276 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11113134, 15262992, 17419807
S276 Phosphorylation P06493 (CDK1) PhosphoSitePlus 11113134
S276 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 11113134, 17419807
S276 Phosphorylation Q13627 (DYRK1A) Signor 15262992
S285 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11113134, 15262992, 17419807
S285 Phosphorylation P06493 (CDK1) PhosphoSitePlus 11113134
S285 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 11113134, 17419807
S285 Phosphorylation Q13627 (DYRK1A) Signor 15262992
S293 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 23651931, 16733250, 15262992
S293 Phosphorylation O76039 (CDKL5) neXtProt 23651931
S293 Phosphorylation P27361 (MAPK3) Signor 15262992
S293 Phosphorylation P28482 (MAPK1) Signor 15262992
S293 Phosphorylation Q13627 (DYRK1A) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 16733250
S295 Phosphorylation neXtProt   PhosphoSitePlus   Signor 16733250, 15262992
S295 Phosphorylation P27361 (MAPK3) Signor 15262992
S295 Phosphorylation P28482 (MAPK1) Signor 15262992
S295 Phosphorylation Q13627 (DYRK1A) neXtProt   PhosphoSitePlus   Signor 16733250
T310 Phosphorylation neXtProt   PhosphoSitePlus   Signor 16733250, 15262992
T310 Phosphorylation Q13627 (DYRK1A) neXtProt   PhosphoSitePlus   Signor 16733250, 15262992
T312 Phosphorylation PhosphoSitePlus 16733250
T312 Phosphorylation Q13627 (DYRK1A) PhosphoSitePlus 16733250
T350 Phosphorylation PhosphoSitePlus   Signor 16945112
T350 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 16945112
T387 Phosphorylation PhosphoSitePlus   Signor 16945112
T387 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 16945112
T445 Phosphorylation PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T260 Phosphorylation HPRD 18510355
S272 Phosphorylation HPRD 11113134
S272 Phosphorylation P06493 (CDK1) HPRD 11113134
S272 Phosphorylation Q00535 (CDK5) HPRD 11113134
S276 Phosphorylation HPRD 11113134
S276 Phosphorylation P06493 (CDK1) HPRD 11113134
S276 Phosphorylation Q00535 (CDK5) HPRD 11113134
S285 Phosphorylation HPRD 11113134
S285 Phosphorylation P06493 (CDK1) HPRD 11113134
S285 Phosphorylation Q00535 (CDK5) HPRD 11113134
S506 Phosphorylation HPRD 15345747
S549 Phosphorylation HPRD 18510355
Site PTM Type PTM Enzyme Score Source PMID
T260 Phosphorylation HPRD 18510355
S272 Phosphorylation HPRD 11113134
S272 Phosphorylation P06493 (CDK1) HPRD 11113134
S272 Phosphorylation Q00535 (CDK5) HPRD 11113134
S276 Phosphorylation HPRD 11113134
S276 Phosphorylation P06493 (CDK1) HPRD 11113134
S276 Phosphorylation Q00535 (CDK5) HPRD 11113134
S285 Phosphorylation HPRD 11113134
S285 Phosphorylation P06493 (CDK1) HPRD 11113134
S285 Phosphorylation Q00535 (CDK5) HPRD 11113134
S464 Phosphorylation HPRD 15345747
S507 Phosphorylation HPRD 18510355


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 N5 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
T260 I260 Biomuta DOID:1612 / breast cancer [ icgc ]
S262 L262 Biomuta DOID:4159 / skin cancer [ cosmic ]
S285 Y285 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S293 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T310 A310 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T310 S310 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T312 K312 Biomuta DOID:1324 / lung cancer [ cosmic ]