iPTMnet Report for P49356 (FNTB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49356 / FNTB_HUMAN
Protein Name Protein farnesyltransferase subunit beta
Gene Name Name: FNTB
Organism Homo sapiens (Human)

PRO ID PR:P49356
DAG View
PRO Name protein farnesyltransferase subunit beta (human)
Definition A protein farnesyltransferase subunit beta that is encoded in the genome of human.
Short Label hFNTB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49356 (FNTB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
Y300 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
K418 Ubiquitination PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation HPRD 17081983
Y300 Phosphorylation HPRD 15592455
T430 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K50 Q50 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K54 N54 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K63 R63 Biomuta DOID:4606 / bile duct cancer [ cosmic ]