iPTMnet Report for P49281 (SLC11A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49281 / NRAM2_HUMAN
Protein Name Natural resistance-associated macrophage protein 2
Gene Name Name: SLC11A2
Synonyms:DCT1,DMT1,NRAMP2;ORFNames:OK/SW-cl.20;
Organism Homo sapiens (Human)

PRO ID PR:P49281
DAG View
PRO Name natural resistance-associated macrophage protein 2 (human)
Definition A natural resistance-associated macrophage protein 2 that is encoded in the genome of human.
Short Label hSLC11A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49281 (SLC11A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation RLIMS-P 27681840
S23 Phosphorylation RLIMS-P 27681840
Y31 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus   RLIMS-P 27681840
S37 Phosphorylation PhosphoSitePlus
S39 Phosphorylation RLIMS-P 27681840
S43 Phosphorylation RLIMS-P 27681840
S56 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S536 Phosphorylation PhosphoSitePlus
Y559 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K17 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K17 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T129 S129 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T129 I129 Biomuta DOID:4159 / skin cancer [ cosmic ]
S176 F176 Biomuta DOID:4159 / skin cancer [ cosmic ]
S176 C176 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]