iPTMnet Report for P49189 (ALDH9A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49189 / AL9A1_HUMAN
Protein Name 4-trimethylaminobutyraldehyde dehydrogenase
Gene Name Name: ALDH9A1
Synonyms:ALDH4,ALDH7,ALDH9;
Organism Homo sapiens (Human)

PRO ID PR:P49189
DAG View
PRO Name 4-trimethylaminobutyraldehyde dehydrogenase (human)
Definition A 4-trimethylaminobutyraldehyde dehydrogenase that is encoded in the genome of human.
Short Label hALDH9A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49189 (ALDH9A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378, 22223895
S9 Phosphorylation PhosphoSitePlus
R15 Methylation PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K298 Acetylation PhosphoSitePlus   UniProt 19608861
K298 Ubiquitination PhosphoSitePlus
K303 Acetylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
K462 Acetylation PhosphoSitePlus
Y476 Phosphorylation PhosphoSitePlus
C484 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 18669648, 20068231
S26 Phosphorylation HPRD 20068231
S33 Phosphorylation HPRD 20068231
S253 Phosphorylation HPRD 20068231
T497 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 F11 Biomuta DOID:1612 / breast cancer [ icgc ]
S253 F253 Biomuta DOID:4159 / skin cancer [ cosmic ]