iPTMnet Report P49185 Mapk8

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P49185 / MK08_RAT
Protein Name	Mitogen-activated protein kinase 8
Gene Name	Name: Mapk8 Synonyms:Jnk1,Prkm8;
Organism	Rattus norvegicus (Rat)

PRO ID	PR:P49185 DAG View
PRO Name	mitogen-activated protein kinase 8 (rat)
Definition	A mitogen-activated protein kinase 8 that is encoded in the genome of rat.
Short Label	rMAPK8
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P49185 (Mapk8) as Substrate

P49185

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	C116	S-Nitrosylation		score1	dbSNO	11121042
	S179	Phosphorylation		score1	PhosphoSitePlus
	T183	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	23139803, 24386130, 29595913, ...21151908, 23554623, 29882093, 25978724, 23372792, 25120278, 23280045
	Y185	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	23139803, 24386130, 29595913, ...21151908, 23554623, 29882093, 25978724, 23372792, 25120278, 23280045
	T188	Phosphorylation		score1	PhosphoSitePlus
	S307	Phosphorylation		score1	RLIMS-P	22362362, 17403295, 32844579
	K308	Acetylation		score1	PhosphoSitePlus

P49185 (Mapk8) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	F1MAL5 (Irs2)	T348	score2	PhosphoSitePlus	17050683
	P06536 (Nr3c1)	S246	score2	PhosphoSitePlus	9482836
	P15146 (Map2)	T1619	score2	PhosphoSitePlus	25309320
	P15146 (Map2)	T1622	score2	PhosphoSitePlus	25309320
	P15146 (Map2)	T1625	score2	PhosphoSitePlus	25309320
	P17325 (Jun)	S73	score2	PhosphoSitePlus	9195981
	P31016 (Dlg4)	S295	score2	PhosphoSitePlus	17988632
	P35570 (Irs1)	S307	score4	PhosphoSitePlus Signor	11606564, 12510059
	P47196 (Akt1)	T450	score1	Signor	16306447
	P84245 (H3-3b)	S29	score2	phospho.ELM	11278789
	Q66H76 (Pxn)	S207	score1	Signor	12853963