iPTMnet Report for P48960 (ADGRE5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48960 / AGRE5_HUMAN
Protein Name Adhesion G protein-coupled receptor E5 precursor
Gene Name Name: ADGRE5
Synonyms:CD97;
Organism Homo sapiens (Human)

PRO ID PR:P48960
DAG View
PRO Name adhesion G protein-coupled receptor E5 (human)
Definition An adhesion G protein-coupled receptor E5 that is encoded in the genome of human.
Short Label hADGRE5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48960 (ADGRE5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N33 N-Glycosylation GlyGen 29741879, 24190977
N38 N-Glycosylation GlyGen 23090970, 24190977
N108 N-Glycosylation GlyGen 29741879, 24190977
T265 O-Glycosylation GlyGen 33214551, 30459171, 34019948, ...35289036, 29351928
K281 Ubiquitination PhosphoSitePlus
N371 N-Glycosylation GlyGen   UniProt 23090970, 24190977, 19349973
T373 O-Glycosylation GlyGen 33214551, 34019948, 35289036, ...29351928
T373 Phosphorylation PhosphoSitePlus
S377 O-Glycosylation GlyGen 33214551, 34019948, 35289036, ...29351928
S377 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
N453 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N454 N-Glycosylation GlyGen 24190977
S531 Phosphorylation PhosphoSitePlus
Y540 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
Y810 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus   UniProt 23186163
T816 Phosphorylation PhosphoSitePlus   UniProt 23186163
T817 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus   UniProt 23186163
T820 Phosphorylation PhosphoSitePlus
T825 Phosphorylation PhosphoSitePlus   UniProt 23186163
S831 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S833 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S815 Phosphorylation HPRD 18578522
S818 Phosphorylation HPRD 18691976, 18578522
T820 Phosphorylation HPRD 20068231
S831 Phosphorylation HPRD 18691976, 18578522, 18767875, ...19651622, 18669648, 20166139, 20068231
S833 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S722 Phosphorylation HPRD 18578522
S725 Phosphorylation HPRD 18691976, 18578522
T727 Phosphorylation HPRD 20068231
S738 Phosphorylation HPRD 18691976, 18578522, 18767875, ...19651622, 18669648, 20166139, 20068231
S740 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S766 Phosphorylation HPRD 18578522
S769 Phosphorylation HPRD 18691976, 18578522
T771 Phosphorylation HPRD 20068231
S782 Phosphorylation HPRD 18691976, 18578522, 18767875, ...19651622, 18669648, 20166139, 20068231
S784 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N33 D33 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
K281 I281 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S377 C377 Biomuta DOID:1324 / lung cancer [ cosmic ]
S725 F725 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S769 F769 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T817 A817 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S818 F818 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]