Protein Information

Cytoscape View

UniProt AC / UniProt ID P48788 / TNNI2_HUMAN
Protein Name Troponin I, fast skeletal muscle
Gene Name Name: TNNI2
Organism Homo sapiens (Human)

PRO ID PR:P48788
DAG View
PRO Name troponin I, fast skeletal muscle (human)
Definition A troponin I, fast skeletal muscle that is encoded in the genome of human.
Short Label hTNNI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P48788 (TNNI2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus
Y80 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation HPRD 4369265
S20 Phosphorylation HPRD 4369265
S118 Phosphorylation HPRD 4369265

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T12 M12 Biomuta DOID:363 / uterine cancer [ icgc ]
R14 P14 Biomuta DOID:1324 / lung cancer [ tcga ]
R14 H14 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S20 T20 Biomuta DOID:363 / uterine cancer [ tcga ]
S90 R90 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S180 F180 Biomuta DOID:1909 / melanoma [ tcga ]