Protein Information

Cytoscape View


UniProt AC / UniProt ID P48775 / T23O_HUMAN
Protein Name Tryptophan 2,3-dioxygenase
Gene Name Name: TDO2
Synonyms:TDO;
Organism Homo sapiens (Human)

PRO ID PR:P48775
DAG View
PRO Name tryptophan 2,3-dioxygenase (human)
Definition A tryptophan 2,3-dioxygenase that is encoded in the genome of human.
Short Label hTDO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48775 (TDO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation phospho.ELM 16094384
S155 Phosphorylation HPRD   PhosphoSitePlus 16094384
T200 Phosphorylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T200 K200 Biomuta DOID:1324 / lung cancer [ cosmic ]