Protein Information

Cytoscape View


UniProt AC / UniProt ID P48740 / MASP1_HUMAN
Protein Name Mannan-binding lectin serine protease 1 precursor
Gene Name Name: MASP1
Synonyms:CRARF,CRARF1,PRSS5;
Organism Homo sapiens (Human)

PRO ID PR:P48740
DAG View
PRO Name mannan-binding lectin serine protease 1 (human)
Definition A mannan-binding lectin serine protease 1 that is encoded in the genome of human.
Short Label hMASP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48740 (MASP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N49 N-Glycosylation UniProt 16335952, 11290788
N178 N-Glycosylation UniProt 16335952, 18596036, 19139490
N385 N-Glycosylation UniProt 16335952, 19139490
Y395 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
N407 N-Glycosylation UniProt 16335952, 11290788
T409 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N385 S385 Biomuta DOID:9256 / colorectal cancer [ tcga ]
Y395 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
Y401 * Biomuta DOID:0070003 / blastoma [ cosmic ]
T409 I409 Biomuta DOID:363 / uterine cancer [ tcga ]