iPTMnet Report for P48740 (MASP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48740 / MASP1_HUMAN
Protein Name Mannan-binding lectin serine protease 1 precursor
Gene Name Name: MASP1
Synonyms:CRARF,CRARF1,PRSS5;
Organism Homo sapiens (Human)

PRO ID PR:P48740
DAG View
PRO Name mannan-binding lectin serine protease 1 (human)
Definition A mannan-binding lectin serine protease 1 that is encoded in the genome of human.
Short Label hMASP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48740 (MASP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N49 N-Glycosylation GlyGen   UniProt 16335952, 11290788
N178 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 23090970, ...19139490, 18596036, 29741879, 29671580
N385 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490, ...29671580, 29741879
Y395 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
N407 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 11290788, ...29741879
T409 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N178 N-Glycosylation PRO 29671580
N385 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N385 S385 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y395 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
Y401 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]