iPTMnet Report for P48739 (PITPNB)
Protein Information
| UniProt AC / UniProt ID | P48739 / PIPNB_HUMAN |
| Protein Name | Phosphatidylinositol transfer protein beta isoform |
| Gene Name | Name: PITPNB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P48739 |
| PRO Name | phosphatidylinositol transfer protein beta isoform (human) |
| Definition | A phosphatidylinositol transfer protein beta isoform that is encoded in the genome of human. |
| Short Label | hPITPNB |
| Category | organism-gene |
P48739 (PITPNB) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K5 | Acetylation | score1 | PhosphoSitePlus | |||
| K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K50 | Acetylation | score1 | PhosphoSitePlus | |||
| K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y57 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C94 | Methylation | score1 | IEDB | 31844290 | ||
| T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K104 | Methylation | score1 | PhosphoSitePlus | |||
| K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R146 | Methylation | score1 | PhosphoSitePlus | |||
| Y154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K155 | Acetylation | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K215 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C230 | Methylation | score1 | IEDB | 31844290 | ||
| R244 | Methylation | score1 | PhosphoSitePlus | |||
| T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 15589696, 16780419 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T256 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S262 | Phosphorylation | score0 | HPRD | 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K252 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K50 | M50 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K54 | N54 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| K60 | T60 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K104 | Q104 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S184 | N184 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View