iPTMnet Report for P48506 (GCLC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48506 / GSH1_HUMAN
Protein Name Glutamate--cysteine ligase catalytic subunit
Gene Name Name: GCLC
Synonyms:GLCL,GLCLC;
Organism Homo sapiens (Human)

PRO ID PR:P48506
DAG View
PRO Name glutamate--cysteine ligase catalytic subunit (human)
Definition A glutamate--cysteine ligase catalytic subunit that is encoded in the genome of human.
Short Label hGCLC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48506 (GCLC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 20068231
S5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S8 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T15 Phosphorylation HPRD 20068231
K16 Acetylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
S70 Phosphorylation HPRD   PhosphoSitePlus 20068231
K73 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
R185 Methylation PhosphoSitePlus
R191 Methylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
C273 Methylation IEDB 31844290
K318 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation HPRD 18767875
S334 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K492 Acetylation PhosphoSitePlus
Y587 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus