iPTMnet Report for P48454 (PPP3CC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48454 / PP2BC_HUMAN
Protein Name Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Gene Name Name: PPP3CC
Synonyms:CALNA3,CNA3;
Organism Homo sapiens (Human)

PRO ID PR:P48454
DAG View
PRO Name serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (human)
Definition A serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform that is encoded in the genome of human.
Short Label hPPP3CC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48454 (PPP3CC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K29 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
C262 Methylation IEDB 31844290
K319 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K29 N29 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S405 L405 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S456 L456 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K460 R460 Biomuta DOID:2531 / hematologic cancer [ cosmic ]