iPTMnet Report for P48378 (RFX2)
Protein Information
| UniProt AC / UniProt ID | P48378 / RFX2_HUMAN |
| Protein Name | DNA-binding protein RFX2 |
| Gene Name | Name: RFX2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P48378 |
| PRO Name | DNA-binding protein RFX2 (human) |
| Definition | A DNA-binding protein RFX2 that is encoded in the genome of human. |
| Short Label | hRFX2 |
| Category | organism-gene |
P48378 (RFX2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score2 | IEDB PhosphoSitePlus UniProt | 23186163, 32387766 | ||
| Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y108 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y373 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S714 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S719 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S10 | L10 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S28 | F28 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y82 | N82 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| Y100 | F100 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S219 | Y219 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] | |
| Y224 | H224 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S719 | F719 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View