Protein Information

Cytoscape View


UniProt AC / UniProt ID P48378 / RFX2_HUMAN
Protein Name DNA-binding protein RFX2
Gene Name Name: RFX2
Organism Homo sapiens (Human)

PRO ID PR:P48378
DAG View
PRO Name DNA-binding protein RFX2 (human)
Definition A DNA-binding protein RFX2 that is encoded in the genome of human.
Short Label hRFX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48378 (RFX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S28 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 32387766
Y82 Phosphorylation PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
Y221 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation IEDB 35494241
S714 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 L10 Biomuta DOID:4159 / skin cancer [ cosmic ]
S28 F28 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y82 N82 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y100 F100 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S219 Y219 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
Y224 H224 Biomuta DOID:4159 / skin cancer [ cosmic ]
S719 F719 Biomuta DOID:4159 / skin cancer [ cosmic ]