iPTMnet Report for P48167 (GLRB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48167 / GLRB_HUMAN
Protein Name Glycine receptor subunit beta precursor
Gene Name Name: GLRB
Organism Homo sapiens (Human)

PRO ID PR:P48167
DAG View
PRO Name glycine receptor subunit beta (human)
Definition A glycine receptor subunit beta that is encoded in the genome of human.
Short Label hGLRB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48167 (GLRB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K28 Acetylation PhosphoSitePlus
K31 Acetylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
N54 N-Glycosylation UniProt 34473954
K117 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
N242 N-Glycosylation UniProt 34473954
Y274 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
Y435 Phosphorylation P12931 (SRC) PhosphoSitePlus   Signor 11882681
K440 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K28 N28 Biomuta DOID:1324 / lung cancer [ cosmic ]
K31 N31 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S125 L125 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T129 A129 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K136 E136 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K136 T136 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S203 I203 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N242 K242 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T277 I277 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T277 A277 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S411 F411 Biomuta DOID:9256 / colorectal cancer [ cosmic ]