iPTMnet Report for P48165 (GJA8)
Protein Information
| UniProt AC / UniProt ID | P48165 / CXA8_HUMAN |
| Protein Name | Gap junction alpha-8 protein |
| Gene Name | Name: GJA8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P48165 |
| PRO Name | gap junction alpha-8 protein (human) |
| Definition | A gap junction alpha-8 protein that is encoded in the genome of human. |
| Short Label | hGJA8 |
| Category | organism-gene |
DAG ViewP48165 (GJA8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T159 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S420 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 21454606 | |
| S428 | Phosphorylation | P17612 (PRKACA) | score2 | neXtProt | 21454606 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S132 | N132 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
| T138 | I138 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T138 | S138 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T159 | I159 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S420 | N420 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
