iPTMnet Report for P48058 (GRIA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48058 / GRIA4_HUMAN
Protein Name Glutamate receptor 4 precursor
Gene Name Name: GRIA4
Synonyms:GLUR4;
Organism Homo sapiens (Human)

PRO ID PR:P48058
DAG View
PRO Name glutamate receptor 4 (human)
Definition A glutamate receptor 4 that is encoded in the genome of human.
Short Label hGRIA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48058 (GRIA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S314 Phosphorylation HPRD   PhosphoSitePlus 20058876
K442 Acetylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
T694 Phosphorylation PhosphoSitePlus
Y695 Phosphorylation PhosphoSitePlus
K760 Ubiquitination PhosphoSitePlus
Y838 Phosphorylation PhosphoSitePlus
T850 Phosphorylation phospho.ELM 10366608
S862 Phosphorylation Q9UQM7 (CAMK2A) , P17252 (PRKCA) , P05129 (PRKCG) , P17612 (PRKACA) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12471040, 10366608, 12536214
Site PTM Type PTM Enzyme Score Source PMID
S314 Phosphorylation HPRD 20058876
T850 Phosphorylation P17252 (PRKCA) HPRD 10366608
S862 Phosphorylation P17612 (PRKACA) , Q13555 (CAMK2G) , P17252 (PRKCA) HPRD 10366608
Site PTM Type PTM Enzyme Score Source PMID
S314 Phosphorylation HPRD 20058876
T416 Phosphorylation PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T416 K416 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T421 K421 Biomuta DOID:263 / kidney cancer [ cosmic ]
K442 R442 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S514 F514 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T850 P850 Biomuta DOID:9256 / colorectal cancer [ cosmic ]