iPTMnet Report for P48048 (KCNJ1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48048 / KCNJ1_HUMAN
Protein Name ATP-sensitive inward rectifier potassium channel 1
Gene Name Name: KCNJ1
Synonyms:ROMK1;
Organism Homo sapiens (Human)

PRO ID PR:P48048
DAG View
PRO Name ATP-sensitive inward rectifier potassium channel 1 (human)
Definition An ATP-sensitive inward rectifier potassium channel 1 that is encoded in the genome of human.
Short Label hKCNJ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48048 (KCNJ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   RLIMS-P 12221079
S44 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15987778, 12878206, 12684516
N117 N-Glycosylation GlyGen   UniProt 10889209
S183 Phosphorylation PhosphoSitePlus   RLIMS-P 12221079
T191 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S201 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   RLIMS-P 12221079
K202 Acetylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y337 Phosphorylation P12931 (SRC) PhosphoSitePlus   Signor 11719519, 19706464, 12217858, ...12556363
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 12221079
S44 Phosphorylation HPRD 8621594
S183 Phosphorylation Q05655 (PRKCD) HPRD 8621594
S201 Phosphorylation HPRD 12221079
S219 Phosphorylation HPRD 8621594
S313 Phosphorylation HPRD 8621594
Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation HPRD 8621594
S164 Phosphorylation Q05655 (PRKCD) HPRD 8621594
S182 Phosphorylation HPRD 12221079
S200 Phosphorylation HPRD 8621594
S294 Phosphorylation HPRD 8621594


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 F25 Biomuta DOID:4159 / skin cancer [ cosmic ]
S44 F44 Biomuta DOID:4159 / skin cancer [ cosmic ]
S164 P164 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S164 C164 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S183 P183 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S183 C183 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T193 M193 Biomuta DOID:3571 / liver cancer [ cosmic ]
T234 A234 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S294 F294 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S313 F313 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]