Protein Information

Cytoscape View


UniProt AC / UniProt ID P48023 / TNFL6_HUMAN
Protein Name Tumor necrosis factor ligand superfamily member 6
Gene Name Name: FASLG
Synonyms:APT1LG1,CD95L,FASL,TNFSF6;
Organism Homo sapiens (Human)

PRO ID PR:P48023
DAG View
PRO Name tumor necrosis factor ligand superfamily member 6 (human)
Definition A tumor necrosis factor ligand superfamily member 6 that is encoded in the genome of human.
Short Label hFASLG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48023 (FASLG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N184 N-Glycosylation PRO 9405425
N250 N-Glycosylation PRO 9405425
N260 N-Glycosylation PRO 9405425


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036459 (hFASLG/iso:FasL/Clv:soluble) Interaction PRO 7536672, 9228058, 9405425
PR:000036782 (hFASLG/iso:FasL/var:F273L) Interaction PR:000000278 (FASLG/iso:FasL/var:F273L) PRO 9405425
PR:000036782 (hFASLG/iso:FasL/var:F273L) altered Interaction PR:P25445 (hFAS) PRO 9405425


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N184 K184 Biomuta DOID:3571 / liver cancer [ cosmic ]