iPTMnet Report for P47989 (XDH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P47989 / XDH_HUMAN
Protein Name Xanthine dehydrogenase/oxidase
Gene Name Name: XDH
Synonyms:XDHA;
Organism Homo sapiens (Human)

PRO ID PR:P47989
DAG View
PRO Name xanthine dehydrogenase/oxidase (human)
Definition A xanthine dehydrogenase/oxidase that is encoded in the genome of human.
Short Label hXDH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P47989 (XDH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation PhosphoSitePlus
T222 Phosphorylation HPRD   PhosphoSitePlus 17081983, 25831123
T222 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 25831123
T311 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K443 Methylation PhosphoSitePlus
K552 Acetylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
Y818 Phosphorylation PhosphoSitePlus
T856 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1111 Phosphorylation PhosphoSitePlus
S1113 Phosphorylation PhosphoSitePlus
T1320 Phosphorylation HPRD   PhosphoSitePlus 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T311 P311 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1111 R1111 Biomuta DOID:9256 / colorectal cancer [ cosmic ]