Protein Information

Cytoscape View


UniProt AC / UniProt ID P47895 / AL1A3_HUMAN
Protein Name Aldehyde dehydrogenase family 1 member A3
Gene Name Name: ALDH1A3
Synonyms:ALDH6;
Organism Homo sapiens (Human)

PRO ID PR:P47895
DAG View
PRO Name aldehyde dehydrogenase family 1 member A3 (human)
Definition An aldehyde dehydrogenase family 1 member A3 that is encoded in the genome of human.
Short Label hALDH1A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P47895 (ALDH1A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K30 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
S424 Phosphorylation HPRD   PhosphoSitePlus 19664994
K430 Ubiquitination PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
Y437 Phosphorylation HPRD   PhosphoSitePlus 19664995
T440 Phosphorylation HPRD   PhosphoSitePlus 20068231
K446 Ubiquitination PhosphoSitePlus
Y492 Phosphorylation PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K33 N33 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
K44 N44 Biomuta DOID:1612 / breast cancer [ tcga ]
K263 Q263 Biomuta DOID:363 / uterine cancer [ tcga ]
K263 N263 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T278 M278 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K430 T430 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
T498 I498 Biomuta DOID:363 / uterine cancer [ tcga ]