Protein Information

Cytoscape View


UniProt AC / UniProt ID P47813 / IF1AX_HUMAN
Protein Name Eukaryotic translation initiation factor 1A, X-chromosomal
Gene Name Name: EIF1AX
Synonyms:EIF1A,EIF4C;
Organism Homo sapiens (Human)

PRO ID PR:P47813
DAG View
PRO Name eukaryotic translation initiation factor 1A, X-chromosomal (human)
Definition A eukaryotic translation initiation factor 1A, X-chromosomal that is encoded in the genome of human.
Short Label hEIF1AX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P47813 (EIF1AX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation PhosphoSitePlus
K5 Acetylation PhosphoSitePlus
K7 Acetylation PhosphoSitePlus
K10 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
T73 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
R82 Methylation PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K94 Sumoylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K3 N3 Biomuta DOID:4362 / cervical cancer [ tcga ]
K7 R7 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K10 E10 Biomuta DOID:1909 / melanoma [ tcga ] DOID:3070 / malignant glioma [ icgc, tcga ]
K56 R56 Biomuta DOID:3571 / liver cancer [ tcga ]
S74 L74 Biomuta DOID:363 / uterine cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
R82 * Biomuta DOID:363 / uterine cancer [ tcga ]
R82 Q82 Biomuta DOID:9256 / colorectal cancer [ icgc ]