iPTMnet Report P47710 CSN1S1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P47710 / CASA1_HUMAN
Protein Name	Alpha-S1-casein precursor
Gene Name	Name: CSN1S1 Synonyms:CASA,CSN1;
Organism	Homo sapiens (Human)

PRO ID	PR:P47710 DAG View
PRO Name	alpha-S1-casein (human)
Definition	An alpha-S1-casein that is encoded in the genome of human.
Short Label	hCSN1S1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P47710 (CSN1S1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S31	Phosphorylation		score3	PhosphoSitePlus UniProt	18847231
	S33	Phosphorylation		score4	phospho.ELM PhosphoSitePlus UniProt	12919330, 17646876, 18847231
	S41	Phosphorylation		score4	phospho.ELM PhosphoSitePlus UniProt	12919330, 17646876, 18847231, ...20068231
	N69	N-Glycosylation		score1	GlyGen	32125861
	S86	Phosphorylation		score3	PhosphoSitePlus UniProt	18847231
	S88	Phosphorylation		score4	PhosphoSitePlus UniProt	17646876, 18847231
	S89	Phosphorylation		score3	PhosphoSitePlus UniProt	18847231
	S90	Phosphorylation		score4	phospho.ELM PhosphoSitePlus UniProt	17646876, 18847231
	S91	Phosphorylation		score3	PhosphoSitePlus UniProt	18847231

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S33	Phosphorylation		score0	HPRD	20068231
	S34	Phosphorylation		score0	HPRD	20068231
	S41	Phosphorylation		score0	HPRD	20068231
	S89	Phosphorylation		score0	HPRD	20068231
	S90	Phosphorylation		score0	HPRD	20068231
	S91	Phosphorylation		score0	HPRD	20068231
	S95	Phosphorylation		score0	HPRD	20068231

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S33	Phosphorylation		score0	HPRD	20068231
	S34	Phosphorylation		score0	HPRD	20068231
	S41	Phosphorylation		score0	HPRD	20068231

P47710 (CSN1S1) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	Q04206 (RELA)	S529	score1	Signor	21232017

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S31	L31	Biomuta		DOID:10534 / stomach cancer [ cosmic ]
S41	*	Biomuta		DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S90	L90	Biomuta		DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]