iPTMnet Report for P46946 (SAE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46946 / COM1_YEAST
Protein Name DNA endonuclease SAE2
Gene Name Name: SAE2
Synonyms:COM1;OrderedLocusNames:YGL175C;ORFNames:G1639;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P46946
DAG View
PRO Name DNA endonuclease SAE2 (yeast)
Definition A protein that is a translation product of the SAE2 gene in yeast.
Short Label ySAE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46946 (SAE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation SGD 24344201
S73 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   SGD 18670132, 16861895
S76 Phosphorylation SGD 23749301
T90 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   RLIMS-P   SGD 31552432, 18670132, 16861895, ...25762720
K97 Sumoylation SGD 33502312
K98 Sumoylation SGD 33502312
S134 Phosphorylation RLIMS-P   SGD 30275497, 24344201
S143 Phosphorylation UniProt 19779198
S177 Phosphorylation BioGRID   SGD 18407956
S179 Phosphorylation RLIMS-P   SGD 30275497, 33491328
K239 Acetylation SGD 24344201
S244 Phosphorylation SGD 24344201
S249 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   RLIMS-P   SGD 18670132, 30275497, 24344201, ...16861895
S265 Phosphorylation SGD 33481703, 33491328
K266 Acetylation SGD 24344201
S267 Phosphorylation P00546 (CDC28) BioGRID   RLIMS-P+   RLIMS-P   SGD   UniProt 22563681, 33481703, 18716619, ...24699249, 31552432, 19595717, 19779198, 20150422, 30275497, 24344201, 33491328
S278 Phosphorylation SGD 24344201
T279 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   RLIMS-P   SGD 18670132, 31552432, 24344201, ...16861895, 25762720
S289 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   SGD 18670132, 16861895


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P46946 (SAE2) T90 P39009 (DUN1) unknown eFIP 25762720
Phosphorylation P46946 (SAE2) T90 P33301 (XRS2) unknown eFIP 25762720
Phosphorylation P46946 (SAE2) T90 P22216 (RAD53) unknown eFIP 25762720