iPTMnet Report for P46939 (UTRN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46939 / UTRN_HUMAN
Protein Name Utrophin
Gene Name Name: UTRN
Synonyms:DMDL,DRP1;
Organism Homo sapiens (Human)

PRO ID PR:P46939
DAG View
PRO Name utrophin (human)
Definition A utrophin that is encoded in the genome of human.
Short Label hUTRN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46939 (UTRN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S10 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S19 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
S84 O-Glycosylation GlyGen 28411811, 30379171, 34725712, ...26853435, 30444036, 29351928, 34019948, 31492838, 35289036, 35254053
T85 O-Glycosylation GlyGen 28411811, 30379171, 34725712, ...26853435, 30444036, 29351928, 34019948, 31492838, 35289036, 35254053
T268 Phosphorylation PhosphoSitePlus
K274 Sumoylation PhosphoSitePlus
S295 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
T360 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
T446 O-Glycosylation GlyGen 28411811, 30379171, 34725712, ...26853435, 30444036, 29351928, 34019948, 31492838, 35289036, 35254053
K464 Ubiquitination PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
T724 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
S825 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S827 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
R896 Methylation PhosphoSitePlus
S926 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
Y1102 Phosphorylation PhosphoSitePlus
T1104 Phosphorylation PhosphoSitePlus
S1258 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19945424
S1258 Phosphorylation Q7KZI7 (MARK2) PhosphoSitePlus   Signor 19945424
K1265 Ubiquitination PhosphoSitePlus
T1266 Phosphorylation PhosphoSitePlus
K1334 Ubiquitination PhosphoSitePlus
R1367 Methylation PhosphoSitePlus
S1405 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1408 Phosphorylation PhosphoSitePlus
R1412 Methylation PhosphoSitePlus
S1415 Phosphorylation PhosphoSitePlus
T1484 Phosphorylation PhosphoSitePlus
S1486 Phosphorylation PhosphoSitePlus
K1551 Ubiquitination PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
S1746 Phosphorylation PhosphoSitePlus
Y1757 Phosphorylation PhosphoSitePlus
S1795 Phosphorylation PhosphoSitePlus
S1796 Phosphorylation PhosphoSitePlus
R1815 Methylation PhosphoSitePlus
S1861 Phosphorylation PhosphoSitePlus
S1866 Phosphorylation PhosphoSitePlus
K1919 Ubiquitination PhosphoSitePlus
S2008 Phosphorylation PhosphoSitePlus   UniProt 24275569
C2098 Methylation IEDB 31844290
S2111 Phosphorylation PhosphoSitePlus
T2112 Phosphorylation PhosphoSitePlus
S2210 O-Glycosylation GlyGen 28411811, 32938750, 30379171, ...34725712, 26853435, 30444036, 29351928, 34019948, 31492838, 35289036, 35254053
S2211 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2213 O-Glycosylation GlyGen 28411811, 30379171, 34725712, ...26853435, 30444036, 29351928, 34019948, 31492838, 35289036, 35254053
S2213 Phosphorylation PhosphoSitePlus
T2222 Phosphorylation PhosphoSitePlus
S2223 Phosphorylation PhosphoSitePlus
S2226 Phosphorylation PhosphoSitePlus
T2255 Phosphorylation PhosphoSitePlus
K2264 Ubiquitination PhosphoSitePlus
Y2285 Phosphorylation PhosphoSitePlus
K2309 Ubiquitination PhosphoSitePlus
Y2355 Phosphorylation PhosphoSitePlus
Y2360 Phosphorylation PhosphoSitePlus
Y2419 Phosphorylation PhosphoSitePlus
S2482 Phosphorylation PhosphoSitePlus
S2567 Phosphorylation PhosphoSitePlus
K2573 Ubiquitination PhosphoSitePlus
Y2599 Phosphorylation PhosphoSitePlus
K2612 Ubiquitination PhosphoSitePlus
S2615 Phosphorylation PhosphoSitePlus
K2645 Ubiquitination PhosphoSitePlus
T2649 Phosphorylation PhosphoSitePlus
S2666 Phosphorylation PhosphoSitePlus
K2684 Ubiquitination PhosphoSitePlus
K2718 Ubiquitination PhosphoSitePlus
K2750 Ubiquitination PhosphoSitePlus
S2760 Phosphorylation PhosphoSitePlus
K2769 Ubiquitination PhosphoSitePlus
K2793 Ubiquitination PhosphoSitePlus
K2826 Ubiquitination PhosphoSitePlus
K2891 Ubiquitination PhosphoSitePlus
K2894 Ubiquitination PhosphoSitePlus
K2971 Ubiquitination PhosphoSitePlus
S3048 Phosphorylation PhosphoSitePlus
K3065 Ubiquitination PhosphoSitePlus
K3069 Ubiquitination PhosphoSitePlus
K3074 Ubiquitination PhosphoSitePlus
K3087 Methylation PhosphoSitePlus
Y3111 Phosphorylation PhosphoSitePlus
Y3151 Phosphorylation PhosphoSitePlus
T3156 Phosphorylation PhosphoSitePlus
T3165 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S3180 Phosphorylation phospho.ELM 18669648
S3182 Phosphorylation phospho.ELM 18669648
Y3197 Phosphorylation PhosphoSitePlus
S3243 Phosphorylation PhosphoSitePlus
S3247 Phosphorylation PhosphoSitePlus
S3254 Phosphorylation PhosphoSitePlus
Y3281 Phosphorylation PhosphoSitePlus
S3297 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S3301 Phosphorylation PhosphoSitePlus
S3304 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S3312 Phosphorylation PhosphoSitePlus
S3358 Phosphorylation PhosphoSitePlus
S3360 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation HPRD 18669648
S10 Phosphorylation HPRD 18669648, 20068231
S295 Phosphorylation HPRD 17081983
T713 Phosphorylation HPRD 20068231
S1405 Phosphorylation HPRD 18669648, 20068231
S2665 Phosphorylation HPRD 20068231
S3297 Phosphorylation HPRD 18669648, 20068231
S3304 Phosphorylation HPRD 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9Y3D6 (FIS1) T34 P46939 (UTRN) increased_association eFIP 35290083


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 I10 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S10 R10 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K47 N47 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S84 Y84 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T268 S268 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S295 I295 Biomuta DOID:363 / uterine cancer [ icgc ]
S295 C295 Biomuta DOID:1324 / lung cancer [ cosmic ]
T664 P664 Biomuta DOID:1324 / lung cancer [ cosmic ]
S825 A825 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S833 F833 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S881 C881 Biomuta DOID:3571 / liver cancer [ cosmic ]
R896 H896 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1725 / peritoneum cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R896 C896 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1367 S1367 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1367 M1367 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1405 F1405 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1415 N1415 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1720 C1720 Biomuta DOID:3571 / liver cancer [ cosmic ]
R1815 K1815 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2008 N2008 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S2008 I2008 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2223 L2223 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S2226 L2226 Biomuta DOID:4159 / skin cancer [ cosmic ]
K2264 R2264 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y2285 H2285 Biomuta DOID:263 / kidney cancer [ cosmic ]
K2309 I2309 Biomuta DOID:363 / uterine cancer [ icgc ]
Y2355 N2355 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y2355 H2355 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y2599 C2599 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S3048 F3048 Biomuta DOID:4159 / skin cancer [ cosmic ]
T3165 I3165 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic ]
S3247 T3247 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S3254 P3254 Biomuta DOID:1319 / brain cancer [ cosmic ]
S3301 L3301 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:2394 / ovarian cancer [ cosmic ]
S3312 L3312 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]