iPTMnet Report for P46926 (GNPDA1)
Protein Information
| UniProt AC / UniProt ID | P46926 / GNPI1_HUMAN |
| Protein Name | Glucosamine-6-phosphate isomerase 1 |
| Gene Name | Name: GNPDA1 Synonyms:GNPI,HLN,KIAA0060; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P46926 |
| PRO Name | glucosamine-6-phosphate isomerase 1 (human) |
| Definition | A glucosamine-6-phosphate isomerase 1 that is encoded in the genome of human. |
| Short Label | hGNPDA1 |
| Category | organism-gene |
DAG ViewP46926 (GNPDA1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K50 | Acetylation | score1 | PhosphoSitePlus | |||
| K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K51 | Acetylation | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K64 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S282 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y287 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K67 | N67 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T161 | P161 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T187 | M187 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y270 | C270 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y270 | H270 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
