iPTMnet Report for P46782 (RPS5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46782 / RS5_HUMAN
Protein Name Small ribosomal subunit protein uS7
Gene Name Name: RPS5
Organism Homo sapiens (Human)

PRO ID PR:P46782
DAG View
PRO Name 40S ribosomal protein S5 (human)
Definition A 40S ribosomal protein S5 that is encoded in the genome of human.
Short Label hRPS5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46782 (RPS5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO   UniProt 19413330, 22223895, 25944712
T2 Acetylation UniProt 19413330, 22223895, 25944712
T2 Phosphorylation HPRD   PhosphoSitePlus 18452278
T14 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 24275569, ...20068231
K18 Sumoylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K22 Sumoylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
T25 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y38 Phosphorylation PhosphoSitePlus
K42 Sumoylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus   UniProt 19608861
K47 Ubiquitination PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
S52 Phosphorylation HPRD   PhosphoSitePlus 20068231
R55 Methylation PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
C66 Methylation IEDB 31844290
C66 S-Nitrosylation dbSNO 26338901
S75 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
R136 Methylation PhosphoSitePlus
S142 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163, 19691289
R145 Methylation PhosphoSitePlus
C155 S-Nitrosylation dbSNO 26338901, 22178444, 19366988, ...18335467
K167 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
C172 S-Nitrosylation dbSNO 19483679, 26338901, 18335467, ...25040305, 22178444, 19366988
K182 Sumoylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
S184 Phosphorylation HPRD 20068231
S185 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K191 Sumoylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K201 Sumoylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036172 (hRPS5/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S52 N52 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R55 L55 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R55 W55 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
Y56 C56 Biomuta DOID:3571 / liver cancer [ cosmic ]
R136 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R136 Q136 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S142 P142 Biomuta DOID:363 / uterine cancer [ icgc ]
C155 R155 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y188 C188 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
K192 N192 Biomuta DOID:1324 / lung cancer [ cosmic ]