iPTMnet Report for P46779 (RPL28)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46779 / RL28_HUMAN
Protein Name Large ribosomal subunit protein eL28
Gene Name Name: RPL28
Organism Homo sapiens (Human)

PRO ID PR:P46779
DAG View
PRO Name 60S ribosomal protein L28 (human)
Definition A 60S ribosomal protein L28 that is encoded in the genome of human.
Short Label hRPL28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46779 (RPL28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 12962325, 22223895, ...25944712
S2 Phosphorylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
C13 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
S14 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
K33 Methylation PhosphoSitePlus
K33 Sumoylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K58 Sumoylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
K101 Sumoylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
Y102 Phosphorylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus   UniProt 20068231
K122 Sumoylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S115 Phosphorylation HPRD 19007248, 20068231, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R11 Q11 Biomuta DOID:4159 / skin cancer [ cosmic ]
S14 P14 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K22 E22 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S37 F37 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K47 N47 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K65 M65 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T80 N80 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T89 R89 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T89 M89 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
S91 N91 Biomuta DOID:4159 / skin cancer [ cosmic ]
S91 R91 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S92 I92 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K101 Q101 Biomuta DOID:1324 / lung cancer [ cosmic ]
R107 C107 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]