iPTMnet Report for P46778 (RPL21)
Protein Information
UniProt AC / UniProt ID | P46778 / RL21_HUMAN |
Protein Name | Large ribosomal subunit protein eL21 |
Gene Name | Name: RPL21 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P46778 |
PRO Name | 60S ribosomal protein L21 (human) |
Definition | A 60S ribosomal protein L21 that is encoded in the genome of human. |
Short Label | hRPL21 |
Category | organism-gene |
P46778 (RPL21) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
R17 | Methylation | score1 | PhosphoSitePlus | |||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y30 | Phosphorylation | score1 | PhosphoSitePlus | |||
R32 | Methylation | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
K43 | Sumoylation | score1 | PhosphoSitePlus | |||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
C56 | Methylation | score1 | IEDB | 31844290 | ||
Y65 | Phosphorylation | score1 | PhosphoSitePlus | |||
N66 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Acetylation | score1 | PhosphoSitePlus | |||
S101 | Phosphorylation | score1 | PhosphoSitePlus | |||
S104 | Phosphorylation | Q96GD4 (AURKB) | score1 | PhosphoSitePlus | 22267324 | |
K107 | Methylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
T124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K129 | Sumoylation | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
R136 | Methylation | score1 | PhosphoSitePlus | |||
T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T29 | I29 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y30 | F30 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
R32 | Q32 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K36 | T36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K50 | R50 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K50 | Q50 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K122 | T122 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
R136 | I136 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T143 | N143 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |