iPTMnet Report for P46776 (RPL27A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46776 / RL27A_HUMAN
Protein Name Large ribosomal subunit protein uL15
Gene Name Name: RPL27A
Organism Homo sapiens (Human)

PRO ID PR:P46776
DAG View
PRO Name 60S ribosomal protein L27a (human)
Definition A 60S ribosomal protein L27a that is encoded in the genome of human.
Short Label hRPL27A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46776 (RPL27A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R12 Methylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus   UniProt 19608861
K47 Ubiquitination PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus   UniProt 19608861
K55 Methylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K59 Sumoylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
R65 Methylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 19369195
C70 S-Nitrosylation dbSNO 26338901
K77 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K110 Acetylation PhosphoSitePlus   UniProt 19608861
K110 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
C144 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K94 N94 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K138 E138 Biomuta DOID:1324 / lung cancer [ cosmic ]