iPTMnet Report for P46414 (Cdkn1b)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P46414 / CDN1B_MOUSE
Protein Name Cyclin-dependent kinase inhibitor 1B
Gene Name Name: Cdkn1b
Organism Mus musculus (Mouse)

PRO ID PR:P46414
DAG View
PRO Name cyclin-dependent kinase inhibitor 1B (mouse)
Definition A cyclin-dependent kinase inhibitor 1B that is encoded in the genome of mouse.
Short Label mCDKN1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46414 (Cdkn1b) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S10 Phosphorylation Q9Z188 (Dyrk1b) , P49615 (Cdk5) , Q61214 (Dyrk1a) phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 24806449, 17726090, 21571010, ...15579463, 22014979, 21194982, 21885849, 29927970, 26528715, 17242355, 15528185, 15010468, 15546868, 20810788, 16391232, 20837141, 12093740
S12 Phosphorylation PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation Q00342 (Flt3) , Q62120 (Jak2) PhosphoSitePlus   RLIMS-P   Signor 28522571, 28295363, 21423214
S106 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23707388
S175 Phosphorylation PhosphoSitePlus
S178 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 12856081
T183 Phosphorylation PhosphoSitePlus
T187 Phosphorylation P49615 (Cdk5) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15075339, 25583987, 12856081, ...21571010, 19584057, 19966802, 11565035, 16229012, 26528715, 20505340, 9192873, 9399644, 20810788, 29927970, 19204084, 27181203
T197 Phosphorylation Q91YS8 (Camk1) PhosphoSitePlus   RLIMS-P+   RLIMS-P 19648963, 20146253, 23707388, ...26344141


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P46414 (Cdkn1b) T187 Q9Z0Z3 (Skp2) unknown eFIP 15075339
Phosphorylation P46414 (Cdkn1b) T187 Q9Z0Z3 (Skp2) unknown eFIP 23255047
Phosphorylation P97377 (Cdk2) T160 P46414 (Cdkn1b) unknown eFIP 26148348