Protein Information

Cytoscape View


UniProt AC / UniProt ID P46379 / BAG6_HUMAN
Protein Name Large proline-rich protein BAG6
Gene Name Name: BAG6
Synonyms:BAT3;
Organism Homo sapiens (Human)

PRO ID PR:P46379
DAG View
PRO Name large proline-rich protein BAG6 (human)
Definition A large proline-rich protein BAT3 that is encoded in the genome of human.
Short Label hBAG6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P46379 (BAG6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S6 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
S26 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
K40 Ubiquitination PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus   UniProt 24275569
S100 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
S113 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17924679
T117 Phosphorylation PhosphoSitePlus   UniProt 24275569
T178 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
S218 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
T251 Phosphorylation PhosphoSitePlus
R344 Methylation PhosphoSitePlus
T350 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S697 Phosphorylation PhosphoSitePlus
Y818 Phosphorylation PhosphoSitePlus
T915 Phosphorylation PhosphoSitePlus
S964 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 19690332, 20068231
S973 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 15302935, ...18669648, 23186163, 19690332, 20068231
T978 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
K1033 Ubiquitination PhosphoSitePlus
K1049 Ubiquitination PhosphoSitePlus
K1052 Ubiquitination PhosphoSitePlus
T1053 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1064 Phosphorylation PhosphoSitePlus
K1072 Ubiquitination PhosphoSitePlus
T1080 Phosphorylation Q9UPZ9 (ICK) PhosphoSitePlus 16954377
S1081 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1084 Phosphorylation PhosphoSitePlus
S1104 Phosphorylation PhosphoSitePlus
Y1116 Phosphorylation PhosphoSitePlus
S1117 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 20068231
T92 Phosphorylation HPRD 20068231
S96 Phosphorylation HPRD 17081983
S104 Phosphorylation HPRD 17081983
S106 Phosphorylation HPRD 20230923
T108 Phosphorylation HPRD 19413330, 17081983
S113 Phosphorylation HPRD 19413330, 18669648, 17924679, ...20068231, 20230923
T350 Phosphorylation HPRD 18669648, 20068231
S964 Phosphorylation HPRD 19651622, 18669648, 18452278, ...20068231, 20230923
S973 Phosphorylation HPRD 19413330, 18088087, 15302935, ...19664994, 19664995, 18452278, 19651622, 18669648, 20058876, 18707149, 20068231
T978 Phosphorylation HPRD 19651622, 20068231
S1039 Phosphorylation HPRD 17081983
Y1042 Phosphorylation HPRD 17081983
T1080 Phosphorylation HPRD 20068231
S1081 Phosphorylation HPRD 18669648, 19664994, 20068231
Y1116 Phosphorylation HPRD 19651622, 17081983
S1117 Phosphorylation HPRD 19413330, 16964243, 20230923, ...15302935, 19664994, 19664995, 19651622, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 20068231
T92 Phosphorylation HPRD 20068231
S96 Phosphorylation HPRD 17081983
S104 Phosphorylation HPRD 17081983
S106 Phosphorylation HPRD 20230923
T108 Phosphorylation HPRD 19413330, 17081983
S113 Phosphorylation HPRD 19413330, 18669648, 17924679, ...20068231, 20230923
T344 Phosphorylation HPRD 18669648, 20068231
S958 Phosphorylation HPRD 20230923, 15302935, 18452278, ...19651622, 18669648, 20068231
S967 Phosphorylation HPRD 19413330, 18088087, 15302935, ...19664994, 19664995, 18452278, 19651622, 18669648, 20058876, 18707149, 20068231
T972 Phosphorylation HPRD 19651622, 20068231
S1033 Phosphorylation HPRD 17081983
Y1036 Phosphorylation HPRD 17081983
T1074 Phosphorylation HPRD 20068231
S1075 Phosphorylation HPRD 18669648, 19664994, 20068231
Y1110 Phosphorylation HPRD 19651622, 17081983
S1111 Phosphorylation HPRD 19413330, 16964243, 20230923, ...15302935, 19664994, 19664995, 19651622, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S832 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 I1 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
T92 S92 Biomuta DOID:1909 / melanoma [ cosmic ]
S113 F113 Biomuta DOID:1612 / breast cancer [ tcga ] DOID:5041 / esophageal cancer [ tcga ]
S1064 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S1117 T1117 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1117 I1117 Biomuta DOID:363 / uterine cancer [ tcga ]