iPTMnet Report for P46063 (RECQL)
Protein Information
| UniProt AC / UniProt ID | P46063 / RECQ1_HUMAN |
| Protein Name | ATP-dependent DNA helicase Q1 |
| Gene Name | Name: RECQL Synonyms:RECQ1,RECQL1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P46063 |
| PRO Name | ATP-dependent DNA helicase Q1 (human) |
| Definition | An ATP-dependent DNA helicase Q1 that is encoded in the genome of human. |
| Short Label | hRECQL |
| Category | organism-gene |
P46063 (RECQL) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C49 | Methylation | score1 | IEDB | 31844290 | ||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K88 | Methylation | score1 | PhosphoSitePlus | |||
| K88 | Sumoylation | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Methylation | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S166 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K171 | Acetylation | score1 | PhosphoSitePlus | |||
| K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K180 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T190 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K193 | Acetylation | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K206 | Acetylation | score1 | PhosphoSitePlus | |||
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y208 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| Y235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K236 | Acetylation | score1 | PhosphoSitePlus | |||
| K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K313 | Methylation | score1 | PhosphoSitePlus | |||
| K380 | Acetylation | score1 | PhosphoSitePlus | |||
| Y399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K452 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C471 | Methylation | score1 | IEDB | 31844290 | ||
| K480 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K487 | Methylation | score1 | PhosphoSitePlus | |||
| K487 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y492 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K509 | Acetylation | score1 | PhosphoSitePlus | |||
| K509 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K514 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K514 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K522 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y559 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K575 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S597 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S603 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T605 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C606 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K613 | Acetylation | score1 | PhosphoSitePlus | |||
| K614 | Acetylation | score1 | PhosphoSitePlus | |||
| K626 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S634 | O-Glycosylation | score1 | GlyGen | 23301498, 27655845, 33214551, ... | ||
| S634 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
| S636 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K637 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K642 | Acetylation | score1 | PhosphoSitePlus | |||
| K643 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S58 | N58 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K180 | Q180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y208 | F208 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K313 | I313 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K452 | R452 | Biomuta | DOID:5041 / esophageal cancer [ tcga ] | |
| C471 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K487 | T487 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K487 | N487 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S597 | F597 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S608 | F608 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K642 | N642 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View