iPTMnet Report for P46063 (RECQL)
Protein Information
UniProt AC / UniProt ID | P46063 / RECQ1_HUMAN |
Protein Name | ATP-dependent DNA helicase Q1 |
Gene Name | Name: RECQL Synonyms:RECQ1,RECQL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P46063 |
PRO Name | ATP-dependent DNA helicase Q1 (human) |
Definition | An ATP-dependent DNA helicase Q1 that is encoded in the genome of human. |
Short Label | hRECQL |
Category | organism-gene |
P46063 (RECQL) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
C49 | Methylation | score1 | IEDB | 31844290 | ||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y61 | Phosphorylation | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K88 | Methylation | score1 | PhosphoSitePlus | |||
K88 | Sumoylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Methylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score0 | HPRD | 20068231 | ||
K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Acetylation | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K180 | Ubiquitination | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
T190 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Acetylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Acetylation | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y208 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y235 | Phosphorylation | score1 | PhosphoSitePlus | |||
K236 | Acetylation | score1 | PhosphoSitePlus | |||
K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
K313 | Methylation | score1 | PhosphoSitePlus | |||
K380 | Acetylation | score1 | PhosphoSitePlus | |||
Y399 | Phosphorylation | score1 | PhosphoSitePlus | |||
K452 | Ubiquitination | score1 | PhosphoSitePlus | |||
C471 | Methylation | score1 | IEDB | 31844290 | ||
K480 | Ubiquitination | score1 | PhosphoSitePlus | |||
K487 | Methylation | score1 | PhosphoSitePlus | |||
K487 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y492 | Phosphorylation | score1 | PhosphoSitePlus | |||
K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
K509 | Acetylation | score1 | PhosphoSitePlus | |||
K509 | Ubiquitination | score1 | PhosphoSitePlus | |||
K514 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K514 | Ubiquitination | score1 | PhosphoSitePlus | |||
K522 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y559 | Phosphorylation | score1 | PhosphoSitePlus | |||
K575 | Ubiquitination | score1 | PhosphoSitePlus | |||
S597 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
S603 | Phosphorylation | score1 | PhosphoSitePlus | |||
T605 | Phosphorylation | score1 | PhosphoSitePlus | |||
C606 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
K613 | Acetylation | score1 | PhosphoSitePlus | |||
K614 | Acetylation | score1 | PhosphoSitePlus | |||
K626 | Ubiquitination | score1 | PhosphoSitePlus | |||
S634 | O-Glycosylation | score1 | GlyGen | 23301498, 27655845, 33214551, ... | ||
S634 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
S636 | Phosphorylation | score0 | HPRD | 20068231 | ||
K637 | Ubiquitination | score1 | PhosphoSitePlus | |||
K642 | Acetylation | score1 | PhosphoSitePlus | |||
K643 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S58 | N58 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K180 | Q180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y208 | F208 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K313 | I313 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K452 | R452 | Biomuta | DOID:5041 / esophageal cancer [ tcga ] | |
C471 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K487 | T487 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K487 | N487 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S597 | F597 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S608 | F608 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K642 | N642 | Biomuta | DOID:363 / uterine cancer [ icgc ] |