iPTMnet Report for P45984 (MAPK9)
Protein Information
UniProt AC / UniProt ID | P45984 / MK09_HUMAN |
Protein Name | Mitogen-activated protein kinase 9 |
Gene Name | Name: MAPK9 Synonyms:JNK2,PRKM9,SAPK1A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P45984 |
PRO Name | mitogen-activated protein kinase 9 (human) |
Definition | A mitogen-activated protein kinase 9 that is encoded in the genome of human. |
Short Label | hMAPK9 |
Category | organism-gene |
P45984 (MAPK9) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
S155 | Phosphorylation | score1 | PhosphoSitePlus | |||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
C163 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
T178 | Phosphorylation | score1 | PhosphoSitePlus | |||
T183 | Phosphorylation | score4 | neXtProt phospho.ELM PRO PhosphoSitePlus RLIMS-P Signor UniProt | 17761173, 31668396, 17192257, ... | ||
T183 | Phosphorylation | O14733 (MAP2K7) | score4 | neXtProt phospho.ELM PhosphoSitePlus Signor | 9890973, 15911620, 11062067 | |
T183 | Phosphorylation | P45985 (MAP2K4) | score1 | Signor | 17761173 | |
Y185 | Phosphorylation | score4 | neXtProt phospho.ELM PRO PhosphoSitePlus RLIMS-P Signor UniProt | 16153436, 31668396, 17192257, ... | ||
Y185 | Phosphorylation | O14733 (MAP2K7) | score1 | Signor | 11062067 | |
Y185 | Phosphorylation | P07949 (RET) | score3 | neXtProt PhosphoSitePlus | 16153436 | |
Y185 | Phosphorylation | P45985 (MAP2K4) | score4 | neXtProt phospho.ELM PhosphoSitePlus Signor | 15911620, 22730327, 11062067 | |
T188 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Acetylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
S292 | Phosphorylation | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
S311 | Phosphorylation | score1 | PhosphoSitePlus | |||
K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y357 | Phosphorylation | score1 | PhosphoSitePlus | |||
N384 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
T404 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus Signor | 11062067 | ||
T404 | Phosphorylation | O14733 (MAP2K7) | score3 | phospho.ELM PhosphoSitePlus | 11062067 | |
T404 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus Signor | 11062067 | |
S407 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus Signor | 11062067 | ||
S407 | Phosphorylation | O14733 (MAP2K7) | score3 | phospho.ELM PhosphoSitePlus | 11062067 | |
S407 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus Signor | 11062067 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T183 | Phosphorylation | score1 | HPRD | 11062067 | ||
T183 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | score2 | HPRD | 16153436, 11062067 | ||
Y185 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | P07949 (RET) | score1 | HPRD | 16153436 | |
Y185 | Phosphorylation | P45985 (MAP2K4) | score1 | HPRD | 11062067 | |
T404 | Phosphorylation | score1 | HPRD | 11062067 | ||
T404 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
S407 | Phosphorylation | score1 | HPRD | 11062067 | ||
S407 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T183 | Phosphorylation | score1 | HPRD | 11062067 | ||
T183 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | score4 | HPRD PhosphoSitePlus | 16153436, 11062067 | ||
Y185 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | P07949 (RET) | score1 | HPRD | 16153436 | |
Y185 | Phosphorylation | P45985 (MAP2K4) | score1 | HPRD | 11062067 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T183 | Phosphorylation | score1 | HPRD | 11062067 | ||
T183 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | score2 | HPRD | 16153436, 11062067 | ||
Y185 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | P07949 (RET) | score1 | HPRD | 16153436 | |
Y185 | Phosphorylation | P45985 (MAP2K4) | score1 | HPRD | 11062067 | |
K236 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T183 | Phosphorylation | score1 | HPRD | 11062067 | ||
T183 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | score2 | HPRD | 16153436, 11062067 | ||
Y185 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
Y185 | Phosphorylation | P07949 (RET) | score1 | HPRD | 16153436 | |
Y185 | Phosphorylation | P45985 (MAP2K4) | score1 | HPRD | 11062067 | |
T404 | Phosphorylation | score1 | HPRD | 11062067 | ||
T404 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 | |
S407 | Phosphorylation | score1 | HPRD | 11062067 | ||
S407 | Phosphorylation | O14733 (MAP2K7) | score1 | HPRD | 11062067 |
P45984 (MAPK9) as PTM Enzyme
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000048328 (hMAPK9/Phos:1) | pT183,pY185 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K56 | N56 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1612 / breast cancer [ cosmic ] | |
S144 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T183 | A183 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K250 | N250 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K251 | T251 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K300 | E300 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S311 | F311 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T404 | M404 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
S407 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |