iPTMnet Report for P45379 (TNNT2)
Protein Information
| UniProt AC / UniProt ID | P45379 / TNNT2_HUMAN |
| Protein Name | Troponin T, cardiac muscle |
| Gene Name | Name: TNNT2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P45379 |
| PRO Name | troponin T, cardiac muscle (human) |
| Definition | A troponin T, cardiac muscle that is encoded in the genome of human. |
| Short Label | hTNNT2 |
| Category | organism-gene |
DAG ViewP45379 (TNNT2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S189 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 24116014 | |
| Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T204 | Phosphorylation | P17252 (PRKCA) , Q99683 (MAP3K5) | score4 | neXtProt PhosphoSitePlus | 12819028, 12832403 | |
| S208 | Phosphorylation | Q99683 (MAP3K5) | score3 | neXtProt PhosphoSitePlus | 12819028 | |
| T213 | Phosphorylation | P04049 (RAF1) | score3 | neXtProt PhosphoSitePlus | 19381846 | |
| S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K290 | Acetylation | score1 | PhosphoSitePlus | |||
| K292 | Acetylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T201 | Phosphorylation | Q99683 (MAP3K5) | score1 | HPRD | 12819028 | |
| S205 | Phosphorylation | Q99683 (MAP3K5) | score1 | HPRD | 12819028 | |
| T210 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 2584239 | |
| T291 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 2584239 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T203 | S203 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |
